DiAGSure® HDV Viral Load Kit

Intent to use:
Hepatitis D virus (HDV) is a small, defective, negative-sense single-stranded RNA virus classified under the genus Deltavirus within Ribozyviria. Eight HDV genotypes have been identified globally, with genotype 1 being most common; genotypes 2 and 4 cause mild disease in East Asia, genotype 3 causes severe hepatitis in South America, and genotypes 5–8 are found only in Africa. It requires co-infection with hepatitis B virus (HBV) to replicate, making it a satellite virus. HDV infection leads to liver inflammation and increases the risk of severe complications such as cirrhosis and hepatocellular carcinoma (HCC). Transmission occurs only in individuals already infected with HBV. Symptoms resemble other acute viral hepatitis infections, including fever, fatigue, nausea, jaundice, and, in severe cases, fulminant hepatitis. The DiAGSure® HDV viral load RT-PCR Kit offers precise, sensitive detection of all HDV variants, enabling early diagnosis and effective infection monitoring.

Key Specifications:
 Quantifies all HDV genotypes (1-8) with traceability to WHO Standard.
 Detects as low as 25 RNA Copies/mL with ≥100% diagnostic sensitivity and specificity.
 Mutation-tolerant assay ensures detection of all HDV genotypes, including variants.
 Ready-to-use Master Mix with internal control minimizes post-PCR handling and error.
Compatible with major real-time PCR instruments for flexible lab integration.

Sample types:
Human Plasma, Serum, whole blood, tissue biopsy and other body fluids and Stool

Product information: