DiAGSure® HLA-B51 Detection Kit

Intent to use:
The DiAGSure® HLA-B51 Detection Kit is a highly sensitive and specific real-time PCR assay developed for the detection of the HLA-B51 allele, a genetic marker significantly associated with Behçet’s disease—an inflammatory disorder that can affect multiple organ systems including the eyes, skin, joints, blood vessels, and nervous system. The presence of HLA-B51 is considered a strong predisposing factor, particularly in populations along the ancient Silk Road, such as the Middle East, Asia, and the Mediterranean. Early identification of this genetic marker is crucial for risk assessment, differential diagnosis, and personalized management of Behçet’s and related autoimmune conditions. The DiAGSure® kit enables accurate genotyping from human genomic DNA, supporting both clinical and research applications. It offers robust performance, seamless integration with major real-time PCR platforms, and is validated for routine use in diagnostic laboratories and autoimmune screening programs.

Key Specifications:
 Accurate identification of HLA-B51 allele, a key genetic marker for Behçet’s disease.
 Supports early diagnosis and risk stratification in autoimmune and inflammatory conditions.
 High sensitivity and specificity, ensuring reliable genotyping results from clinical DNA samples.
Aids in differential diagnosis, especially in complex multi-system inflammatory syndromes.
 Compatible with leading real-time PCR instruments, allowing smooth lab workflow integration.

Sample types:
Whole Blood, EDTA Plasma, Skin eschar.

Product information: